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Condolences on the passing of the late Professor Dr. Muhammad Ibrahim Al-Shari, may God have mercy on him.

تتقدم أسرة كلية الطب البيطري وعلى رأسها

الاستاذ الدكتور/ ايناس احمد عبد الحافظ عميد الكلية

والسادة الوكلاء والسادة أعضاء هيئة التدريس ومعاونيهم والجهاز الإداري

بخالص العزاء في وفاة المغفور له بإذن الله

ا.د/ محمد إبراهيم الشري

الأستاذ المتفرغ بقسم الباثولوجيا بكلية الطب البيطري

ووالد ا.د/ تيمور محمد إبراهيم الشرى الأستاذ ورئيس قسم التوليد والتناسل والتلقيح الاصطناعي ووالد ا.م.د / شيم محمد إبراهيم الشرى الأستاذ المساعد  بقسم طب الطيور والأرانب

 صلاة الجنازة في مسجد البقلي والمدافن بطريق المطار

انا لله وانا اليه راجعون تغمد الله الفقيد بواسع رحمته

وغفر له واسكنه فسيح جناته والهم أهله الصبر والسل

Professor Doaa Mohamed Mokhtar, Professor of Cell and Tissue Medicine, and Dr. Mohamed Ramadan Farghaly, Lecturer in the Department of Animal Health and Environmental Health, have been included in Stanford University's ranking of the top 2% of most influe

ا.د/ايناس احمد عبد الحافظ  

عميد الكلية 

بخالص التهاني القلبية إلى كلا من

 ا.د/ دعاء محمد مختار استاذ الخلية والأنسجة

د/ محمد رمضان فرغلي المدرس بقسم صحة الحيوان والصحة البيئية

بمناسبة إدراج سيادتهما كأفضل 2% من العلماء الأكثر تأثيرا ضمن تصنيف جامعة ستانفورد للعام الرابع  على التوالي

مع خالص الأمنيات بدوام التقدير والنجاح

Impact of urea as a protein substitute in growing camel rations on performance, nitrogen balance, blood metabolites, immune status, and rumen fermentation

Research Abstract
Background
Urea, a non-protein nitrogen, is a widely used, affordable, and readily available protein supplement.
Aim
This study aimed to investigate the effect of urea as a protein substitute in growing camel rations on performance, digestion, nitrogen balance, blood metabolites, antioxidant status, immunity, inflammatory markers, and rumen fermentation, and to identify its ideal inclusion level.
Methods
Twenty Dromedary camels (Camelus dromedarius) with one hump, originally from Egypt, aged around 30 months, averaging 305.25 ± 2.15 kg in body weight, were randomly allocated to four treatments with 5 animals in each group. The crude protein of the camel diets was substituted with urea as follows: 0 (0% urea, T1), 33% (1.4% urea, T2), 50% (2.1% urea, T3), and 66% (2.8% urea, T4).
Results
Weight gain and feed conversion were significantly improved (p < 0.05) in camels fed with 33% urea substitution …
Research Authors
Heba A Nasr, Ghada SE Abdel-Raheem, Abdelbaset Ahmed, Walaa MS Gomaa
Research Date
Research Department
Department of Animal and Clinical Nutrition
Research Journal
Open Veterinary Journal
Research Member
Ghada Sharaf al-Din Abdel-Rahim
Heba abd-el baset nasr
Abdel-Baset Nasr Sayed Ahmed
Walaa Mohamed Sayed Jomaa
Research Pages
5912
Research Publisher
Eldaghayes Publisher
Research Vol
15
Research Year
2025

Synergistic Effects of Thyroxine and Nano-Melatonin on Post-Thaw Sperm Quality, Antioxidant Defence and Fertility of Cryopreserved Simmental Bull Semen

Research Abstract

Background

Cryopreservation induces oxidative stress and functional damage in spermatozoa, negatively affecting sperm quality and fertility. Nano-melatonin (NM) and thyroxine (T) have been suggested as potential cryoprotective agents because of their antioxidant and metabolic regulatory properties.

Objectives

This study aimed to evaluate the effects of thyroxine and nano-melatonin supplementation in semen extenders on post-thaw sperm quality, antioxidant status, apoptosis, and fertility of cryopreserved Simmental bull semen.

Methods

Ninety-six ejaculates were collected from six healthy Simmental bulls over 8 weeks. Semen samples were pooled and diluted with extenders supplemented with T (0.5, 0.75 and 1 µg/dL), NM (30, 45 and 60 µg/dL), or their combinations. Post-thaw sperm motility, kinematics, viability, acrosome integrity, plasma membrane integrity, mitochondrial membrane potential, DNA integrity, antioxidant parameters, lipid peroxidation, apoptosis-like changes, and conception rates were evaluated.

Results

The combined thyroxine and nano-melatonin treatment (T0.5 + NM30) significantly improved (p < 0.05) sperm motility and velocity parameters (VAP, VCL and VSL) compared with the other groups. This group also exhibited significantly higher viability, acrosome integrity, plasma membrane integrity, mitochondrial membrane potential, and DNA integrity. Antioxidant activity (GPx, SOD and TAC) was significantly enhanced, whereas MDA levels and late apoptotic sperm cells were reduced in the nano-melatonin-treated and combination groups, particularly T0.5 + NM30. Furthermore, conception rates were significantly increased in the NM30 (77.14%) and T0.5 + NM30 (82.86%) groups compared with the control group (48.57%).

Conclusions

Supplementation of semen extenders with thyroxine and nano-melatonin, particularly the T0.5 + NM30 combination, improved post-thaw sperm quality, antioxidant defence and fertility of cryopreserved Simmental bull semen, indicating a synergistic cryoprotective effect during semen cryopreservation.

Research Authors
Marwa Abonagy, Ahmed Arisha, Maha Salama, Mohey Ashour, Mustafa Shukry, Sameh Shedeed, Ahmed Shehabeldin, Nagi El-Shafai, Zein Ibrahim, Shawky Mahmoud, Michel Saad, Ahmed Alameen, Rasha Yassin Elkhidr, Osama Hassan Alif, Arafat Khalphallah, Enas Elmeligy,
Research Date
Research Department
Department of Animal Medicine
Research File
Synergistic Effects of Thyroxine and Nano‐Melatonin on Post‐Thaw Sperm Quality, Antioxidant Defence and Fertility of Cryopreserved Simmental Bull Semen.pdf (1.56 MB)
Research Journal
Veterinary Medicine and Science
Research Member
Arafat Abdellah Abdelrahman Khalphallah
Enas Refaat Mohammed Hassan Aly
Research Pages
e71252
Research Publisher
https://onlinelibrary.wiley.com/
Research Rank
Q1
Research Vol
12 (6)
Research Website
https://onlinelibrary.wiley.com/doi/10.1002/vms3.71252
Research Year
2026
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